National & International Grants
Nationally Funded Projects 2019/2020
Implementation of the first validated diagnostic peptide-MHC multimer test for measuring Sars-CoV-2 T cell memory (Covid-2-tag)
CCRI responsible principle investigator: René Geyeregger
Grant from the Austrian Research Promotion Agency (FFG), KLIPHA-COVID 19
Duration: 01/05/2020 to 30/04/2021
SARS-CoV-2 infections and virus shedding in pediatric patients displaying different risk constellations
CCRI responsible principle investigator: Thomas Lion
Grant from the City of Vienna, Bürgermeisterfonds
Duration: 01/09/2020 to 28/02/2021
Detailed characterization of the cellular immune response to SARS-CoV-2 infection
CCRI responsible principle investigator: René Geyeregger
Grant from the Vienna Science and Technology Fund (WWTF), WWTF-Covid 19 Rapide Response
Duration: 01/06/2020 to 30/06/2021
Art4Science
CCRI responsible principle investigator: Eva König
Grant from the Austrian Science Fund (FWF), Science Communication
Duration: 01/05/2020 to 30/12/2021
A novel gene defect affecting actin dynamics reveals unexplored links between immunodeficiency and autoinflammation
CCRI responsible principle investigator: Jana Block (supervisor: Kaan Boztug)
Grant from the Austria Academy of Sciences (ÖAW), DOC fellowship
Duration: 01/03/2020 to 28/02/2022
Automated minimal residual disease assessment in childhood acute myeloid leukemia (MYEFLOW)
CCRI responsible principle investigator: Margarita Maurer-Granofszky (group leader: Michael Dworzak)
Grant from the Vienna Business Agency, From Science to Products 2019
Duration: 01/01/2020 to 31/12/2022
Identifying the Ewing Sarcoma cell-of-origin by cross-species enhancer activity analysis
CCRI responsible principle investigator: Sarah Grissenberger (supervisor: Martin Distel)
Grant from the Austria Academy of Sciences (ÖAW), DOC fellowship
Duration: 01/12/2019 to 31/05/2022
CD Laboratory for "Next generation CAR-T cells"
CCRI coordinator: Manfred Lehner
Christian Doppler Association, Christian Doppler Lab
Duration: 01/11/2019 to 31/10/2026
Detection and prognostic relevance of DUX4 rearrangements in childhood leukemia
CCRI responsible principal investigator: Sabine Strehl
Grant from the Austrian National Bank (OeNB), Jubiläumsfonds
Duration: 01/08/2019 to 31/01/2022
Advancing Liquid Biopsies for Monitoring and Personalized Treatment of Children with Neuroblastomas (LIQUIDHOPE)
CCRI responsible principal investigator: Sabine Taschner-Mandl
Grant from the Austrian Science Fund (FWF), TRANSCAN-2 JTC 2020
Duration: 01/04/2019 to 31/03/2022
Find tumor immune evasion strategies by cellular barcoding
CCRI responsible principal investigator: Eva König
Grant from the Austrian Science Fund (FWF), Stand Alone Project
Duration: 15/03/2019 to 15/03/2023
Ultra-high-risk pediatric cancer - combinatorial drivers and therapeutic targets for precision medicine
CCRI responsible principal investigator: Sabine Taschner-Mandl
Grant from the Vienna Science and Technology Fund (WWTF), Life Sciences 2018
Duration: 01/03/2019 to 28/02/2022
Targeting the Ewing sarcoma microenvironment to overcome resistance to therapy
CCRI responsible principal investigator: Eleni Tomazou
Grant from the Vienna Science and Technology Fund (WWTF), Life Sciences 2018
Duration: 01/03/2019 to 28/02/2023
Analysis of temporal and spatial Ewing sarcoma tumor evolution during chemotherapy and validation of its clinical implication
CCRI responsible principal investigator: Eleni Tomazou
Grant from the Austrian National Bank (OeNB), Jubiläumsfonds
Duration: 01/09/2018 to 31/08/2021
Phylogenetic analysis of primary and disseminated tumor cells to reconstruct the metastatic route of relapsed neuroblastomas
CCRI responsible principal investigator: Reza Abbasi
Grant from the Ingrid Shaker Nessmann Krebsforschungsvereinigung (ISNK), Forschungsförderung 2018
Duration: 01/02/2018 to 31/01/2019
Platform supporting an integrated analysis of image and multiOMICs data based on liquid biopsies for tumor diagnostics (VISIOMICS)
Labdia Coordinator: Sabine Taschner-Mandl, Peter Ambros
Grant from the Austrian Research Promotion Agency (FFG), COIN Programme
Duration: 01/11/2017 to 31/12/2019
Role of stress granules in Ewing sarcoma susceptibility
CCRI responsible principal investigator: Heinrich Kovar
Grant from the Austrian Science Fund (FWF), Stand Alone Project
Duration: 01/06/2017 to 31/05/2020
Establishing a zebrafish disease model drug screening platform, (Danio4Can)
CCRI responsible principal investigator: Martin Distel
Grant from the Austrian Research Promotion Agency (FFG), R&D Infrastrukturförderung, 1st Call
Duration: 01/05/2017 to 31/05/2019
Ewing sarcoma – an enhancer disease?
CCRI responsible principal investigator: Eleni Tomazou
Grant from the Austrian Science Fund (FWF), Elise Richter Programme
Duration: 01/01/2016 to 31/12/2020
Permanent consequences in childhood Langerhans cell histiocytosis
CCRI responsible principal investigator: Milen Minkov
Grant from the Austrian National Bank (OeNB), Jubiläumsfonds
Duration: 01/09/2015 to 31/05/2019
Internationally Funded Projects 2019/2020/2021
Functional Interrogation of Non-coding DNA Sequences in leukemia development and drug resistance (FIND-seq)
CCRI responsible principal investigator: Davide Seruggia
European Commission Grant - ERC-2020-STG
Duration 01/01/2021 to 31/12/2025
Integrated and standardized NGS workflows for Personalised therapy (INSTAND-NGS4P)
CCRI partners: Ruth Ladenstein, Kaan Boztug
Coordinator: Kurt Zatloukal (Medical University Graz)
European Commission Grant – H2020-SC1-BHC-10-2019
Duration: 01/01/2020 to 31/12/2024
Charting key molecules and mechanisms of human immune Dysregulation (iDysChart)
CCRI responsible principal investigator: Kaan Boztug
European Commission Grant - ERC-2018-COG
Duration 06/01/2019 to 31/05/2024
Childhood Leukemia: Overcoming distance between South America and Europe Regions (CLOSER) CCRI partner: Oskar Haas
Coordinator: Mireia Camos (Hospital Sant Joan de Déu de Barcelona)
European Commission Grant - H2020-SC1-2018
Duration: 01/01/2019 to 31/12/2023
European Joint Programme on Rare Diseases (EJP RD)
CCRI responsible principal investigator: Ruth Ladenstein
European Commission Grant - H2020-SC1-BHC-2018-2020
Duration: 01/01/2019 – 31/12/2023
Molecular mechanisms of melflufen in osteosarcoma cells (Oncopeptides)
CCRI responsible principal investigators: Thomas Lion, Konstantin Byrgazov
Oncopeptides Preclinical Grant
Duration: 01/01/2019 to 31/12/2019
Comprehensive heatmap for TKI-resistance of mutations in BCR-ABL1 kinase domain
CCRI responsible principal investigators: Thomas Lion, Konstantin Byrgazov
Incyte Corporation - Incyte open calls
Duration: 01/01/2019 to 31/03/2020
Developmental hierarchy in LCH
CCRI responsible principal investigator: Caroline Hutter
Histiocytosis Association Grant
Duration: 01/01/2019 to 31/12/2019
PRedictive In-silico Multiscale Analytics (PRIMAGE)
CCRI responsible principal investigator: Ruth Ladenstein
European Commission Grant – Call H2020-SC1-DTH-2018-2020
Duration: 01/12/2018 to 30/11/2022
Integrated European Network on cGvHD
CCRI responsible principal investigator: Anita Lawitschka
European Commission Grant – COST Action
Duration: 31/08/2018 to 30/08/2022
ERN-PAEDCAN-CEF-Telecom Y1 & Y2
CCRI Coordinator: Ruth Ladenstein
European Commission Grant – Call CEF-TC-2017-2
Duration: 01/05/2018 to 31/08/2021
ERN-PAEDCAN Partner: Paediatric Rare Tumours Network - European Registry (PARTNER)
CCRI responsible principal investigator: Ruth Ladenstein
European Commission Grant – Call CEF-TC-2017-2
Duration: 01/01/2018 to 30/06/2021
Paediatric Cancer European Reference Network (ERN PaedCan)
CCRI Coordinator: Ruth Ladenstein
Grant from the European Consumers, Health, Agriculture and Food Executive Agency (CHAFEA)
Duration: 01/03/2017 to 28/02/2022
ITCC Pediatric Preclinical POC Platform (ITCCP4)
CCRI partner: Heinrich Kovar
Coordinator: Stefan Pfister (Deutsches Krebsforschungszentrum DKFZ, Germany)
European Commission Grant – H2020 Innovative Medicines Initiative
Duration: 01/01/2017 to 31/12/2021
Children’s Liver Tumour European Research Network (ChiLTERN)
CCRI partner: Heidrun Boztug
Coordinator: Keith Wheatley (University of Birmingham, UK)
European Commission Grant - H2020-PHC-2014-2015
Duration: 01/01/2016 to 31/12/2020
Optimized diagnostics for improved treatment stratification in invasive fungal diseases (FUNGITECT)
CCRI/Labdia Coordinator: Thomas Lion
European Commission Grant – FP7 Cooperation Project
Duration: 01/01/2014 to 31/01/2019
EURO EWING Consortium – International clinical trials to improve survival from Ewing sarcoma (EEC)
CCRI partner: Heinrich Kovar
Coordinator: Jeremy Whelan (University College London, UK)
European Commission Grant – FP7 Cooperation Project
Duration: 01/01/2014 to 30/09/2019