Bioinformatician (m/f/d) in Bioinformatics Core Unit

Bioinformatician (m/f/d) in Bioinformatics Core Unit


Bioinformatics Core Unit

Working hours:
Full time

We are extending our bioinformatics team and are seeking for an enthusiastic bioinformatician who would like to build and advance their career in translational cancer genomics.

You will conduct analyses of genomics data from childhood cancers and cancer predisposition syndromes in close collaboration with molecular biologists, geneticists, pediatric oncologists and other bioinformaticians. Examples of recent projects include genomic, transcriptomic and epigenomic analyses of pediatric leukemia and solid tumors on primary tumors and liquid biopsies, and the analysis of experimental model systems (e.g. Sheffield et al Nature Medicine 2017; Halbritter et al Cancer Discovery 2019; Kalinichenko A et al Blood 2021). The CCRI is also involved in several large-scale national and international research collaborations.

The position is focused on acting as an active member of the bioinformatics core unit and as a service provider for the different research groups at the CCRI but also offers opportunities for independent and applied research of novel bioinformatics methodologies related to the CCRI research programs.

Your responsibilities

  • Lead bioinformatics design and analyses of transcriptomics datasets from bulk and single-cell RNA sequencing and their integration with other data sources and *-omics data as required.
  • Customize genomic analysis pipelines for advanced cancer research applications.
  • Provide bioinformatics support to different research groups at the CCRI and provide guidance/supervision to group-associated bioinformaticians.
  • Evaluate new open-source and commercial software packages for analysis, annotation, and interpretation of sequencing data, and integrate with existing bioinformatics and genomics databases.
  • Document all procedures reliably and actively communicate results to other bioinformaticians, researchers and clinicians.
  • Keep up-to-date with current developments in the field, contribute ideas and help in designing novel cutting-edge genomics projects.
  • Desirable: conduct own research and develop novel methodologies and algorithms for analysis, integration and interpretation of NGS data and evaluate these in close collaboration with CCRI researchers; lead or contribute to grant applications.

Your profile

  • Master's or PhD degree or proven track record in bioinformatics, computational biology or data analysis
  • Experience in applied NGS data analysis such as Transcriptomics (RNA-seq, scRNA-seq), Genomics (WGS/WES) and Epigenomics (WGBS, ChIP-seq, ATAC-seq); additional experience with other omics methods is a plus.
  • Demonstrable experience in programming languages required for data analysis (R and/or Python); experience with other programming languages is of advantage.
  • Proficiency with Linux/Unix; experience with HPC is of advantage.
  • Desirable: Experience building and maintaining bioinformatics tools/pipelines; experience with scientific software development is of advantage.
  • A solid foundation in statistics
  • Ability to work independently, self-motivated and creatively
  • Excellent communication skills in English (German not required) with the ability to communicate effectively at different levels of technical knowledge
  • Ability to assess new developments in the field and apply them efficiently

Our offer

  • A meaningful, inspiring, and international environment
  • An outstanding working atmosphere in a strong team with excellent research and development opportunities
  • Access to state-of-the-art infrastructure
  • Flexible working hours and other great benefits
  • Great location in the center of Vienna, a capital of biomedical research in Europe with excellent quality of life
  • A fair and attractive salary package starting at € 3.000,-- gross (14x per year) on full-time basis with a view to increase based on your qualification and experience

Who we are

The St. Anna Children’s Cancer Research Institute (CCRI), located in the center of Vienna, the world’s most livable city and one of Europe’s most important places for biomedical research and life sciences, is an international and multidisciplinary competence center striving to improve treatment of children and adolescents with cancer by connecting translational and clinical research with open-minded exploration of basic disease mechanisms. Through close cooperation between clinic and research, the CCRI provides an ideal environment for cutting-edge research and its translation into clinical practice. To achieve our ultimate goal of advancing the well-being of patients, the CCRI constantly pushes scientific boundaries and strongly promotes close collaboration and exchange with external institutions like the Medical University of Vienna, CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, the Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA) and the Institute of Molecular Pathology (IMP).

The CCRI is an equal opportunity employer. We value diversity and are committed to providing a work environment
of mutual respect to everyone regardless of ethnicity, religion, national origin, age, gender identity or expression,
disability, or any other characteristic protected by applicable laws, regulations and ordinances.

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Your application

Please send your application via email to Kaan Boztug, Applications should at least contain your Curriculum Vitae, a cover letter, list of publications (please mark / explain your three top contributions), and the contact details of three references.