(04.02.2021) Childhood Cancer often still lacks awareness. This is not only because people might feel uncomfortable dealing with such a sad topic – like an affected mother told us. It is also due to its rare nature. In fact, pediatric cancer is not a single disease, but rather a number…
World Cancer Day, February 4th: Childhood cancer – a rare, but devastating diagnosis
Conquering Cancer - Mission Possible
(28.01.2021) Today, Thursday 28th of January, CCRI´s committed childhood cancer ambassador Prof. Ruth Ladenstein, member of the EU mission cancer board will raise Europe-wide awareness about childhood cancer twice in one day. In the morning (approx. 10:30am) Prof. Ladenstein will inform on the next planned steps of the EU initiative…
From Harvard to Vienna: Epigenetics expert Davide Seruggia joins St. Anna CCRI as Principal Investigator
(27.01.2021) Davide Seruggia, PhD, ERC Starting Grant awardee, leaves Harvard School of Medicine to start his own research group at St. Anna Children’s Cancer Research Institute (St. Anna CCRI). The young scientist is looking forward to investigate epigenetic mechanisms of gene regulation in childhood leukemia to discover truly innovative treatment…
New approach explains how protein complexes regulate cancer genes
(Vienna, 22.02.2021): While NUP98-fusion proteins have been shown to cause leukaemia, the molecular mechanisms have so far been unknown. In a recently published study in Nature Structural & Molecular Biology led by Vetmeduni Vienna, with the participation of St. Anna Children's Cancer Research Institute and others, researchers have now been…
YAP/TAZ targeting reduces Ewing sarcoma metastasis
A recent publication from Heinrich Kovar´s group at St. Anna Children´s Cancer Research Institute (CCRI) and colleagues reveals that inhibition of the YAP/TAZ pathway may prevent Ewing sarcoma cell dissemination and metastasis, thus presenting a promising new therapeutic target for a disease with a long-standing stagnant poor clinical outcome. …
CCRI Christian-Doppler Lab wins BOKU Invention of the Year 2020 Award
(Vienna, 18.12.2020) Each year, the University of Natural Resources and Life Sciences (BOKU), Vienna awards the most outstanding invention. In 2020, the prize went to our co-inventors from the external module of CCRI´s Christian-Doppler Laboratory for Next Generation CAR T Cells, DI Michael Traxlmayr, PhD, and Charlotte Zajc, PhD, with…
New method of Coronavirus Decontamination
(Vienna, 17.12.2020) Prof. Thomas Lion, MD, PhD, MSc, of St. Anna Children’s Cancer Research Institute in Vienna and Doc. Ing. Vladimir Scholtz, PhD, of the University of Chemistry and Technology in Prague, are selected for the first international FWF corona urgent funding. The focus of their research project is on…
Video: Early cancer diagnosis seems crucial in children with immune defect
(Vienna, 03.12.2020) CD27/CD70 deficiencies can lead to cancer in small children: “If diagnosed at an early stage, the majority of these patients are responsive to the hematopoietic stem cell treatment”, says Co-first author Sevgi Köstel Bal, MD, Phd, St. Anna Children's Cancer Research Institute (CCRI)’s, in a video statement on…
Cancer in children with rare inborn immune defect: High cure rate if treated early
(Vienna, 03.12.2020) New research data highlight a marked predisposition to lymphoma, a type of cancer, in children harboring specific gene mutations. A significant fraction of these rare mutations also cause inborn immune defects associated with recurrent infections. Collaborating closely with leading centers across the world, researchers investigated patients bearing recently…
Selected for funding: Training a new generation of childhood cancer scientists
(Vienna, 24.11.2020) St. Anna Children’s Cancer Research Institute is part of a European Marie Sklodowska-Curie Actions Innovative Training Network ITN. Being awarded with this grant, Prof. Heinrich Kovar, PhD, is looking forward to train an international PhD student within the VAGABOND program. The successful candidate will investigate druggable molecular pathways…