Immune cells out of control: how lethal hyperinflammation  emerges from a novel gene defect

Immune cells out of control: how lethal hyperinflammation emerges from a novel gene defect

(Vienna, 16.04.2021) Scientists at St. Anna Children’s Cancer Research Institute, together with their collaborators from Finland and Sweden, discover a novel subtype of a genetic disease: genetically determined deficiency of the protein RhoG abrogates the normal cytotoxic function of specific immune cells, causing hemophagocytic lymphohistiocytosis (HLH). These new findings may…

How to improve image analyses of cancer cells

How to improve image analyses of cancer cells

(Vienna, 15.04.2021) New publication on artificial intelligence: Scientists at St. Anna Children‘s Cancer Research Institute present novel insights on automated image analyses of cancer cells. Based on their results the researchers recommend the creation of artificial images to train deep neural networks. Furthermore, they propose methods to effectively segment complex…

Mutations in SYK cause severe immune disorder with cancer predisposition

Mutations in SYK cause severe immune disorder with cancer predisposition

(Vienna, 29.03.2021) Researchers have deciphered the underlying mechanism of a previously unknown immune disorder that causes severe immune dysfunction involving the intestine, skin, and nervous tissues. The international research team could demonstrate that this disorder is caused by mutations affecting the signaling molecule termed spleen tyrosine kinase (SYK). The newly…

Alex’s Lemonade Stand Foundation Crazy 8 Initiative Award goes to Vienna: Tracking the tumor origin to cure childhood cancer

Alex’s Lemonade Stand Foundation Crazy 8 Initiative Award goes to Vienna: Tracking the tumor origin to cure childhood cancer

(Vienna, 16.03.2021) The project “Tracking the origin of Ewing sarcoma (…)” coordinated by St. Anna Children’s Cancer Research Institute, has been selected for the prestigious Crazy 8 Initiative Award. With this funding, Viennese scientists aim to elucidate the still unsolved mystery of the origin and development process of pediatric bone…

Art4Science Panel Discussion: Science and Sensuality. Can Art convey Knowledge?

Art4Science Panel Discussion: Science and Sensuality. Can Art convey Knowledge?

(Vienna, 25.02.2021) TODAY at 18:30 St. Anna Children's Cancer Research Institute (CCRI) is organizing a panel discussion series together with the Wiener Zeitung as part of our FWF project art4science (www.art4science.at).  [The panel discussion is in German.] Art and science are considered two opposing disciplines from which society expects completely…

International Childhood Cancer Day: New study on leukemia treatment

International Childhood Cancer Day: New study on leukemia treatment

(Vienna, 15.02.2021) Feb 15 is International #ChildhoodCancerDay, a global collaborative campaign to raise awareness about childhood cancer. Scientists at St. Anna Children’s Cancer Research Institute and affiliated clinicians work all year long to improve the chances for children with cancer. A great example is Prof. Christina Peters who recently published…

February 11 is #WomenScienceDay – a reminder that women  play a critical role in science

February 11 is #WomenScienceDay – a reminder that women play a critical role in science

(11.02.2021) At St. Anna Children’s Cancer Research Institute, almost 70% of our scientists are female. Promoting positive role models, with excellent female scientists in PI positions, we strive to empower women and girls to lead and innovate. Let us raise awareness against stereotypes and stand up together for equal opportunities and…