(Vienna, 22.02.2021): While NUP98-fusion proteins have been shown to cause leukaemia, the molecular mechanisms have so far been unknown. In a recently published study in Nature Structural & Molecular Biology led by Vetmeduni Vienna, with…
New approach explains how protein complexes regulate cancer genes
YAP/TAZ targeting reduces Ewing sarcoma metastasis
A recent publication from Heinrich Kovar´s group at St. Anna Children´s Cancer Research Institute (CCRI) and colleagues reveals that inhibition of the YAP/TAZ pathway may prevent Ewing sarcoma cell dissemination and metastasis, thus presenting a…
CCRI Christian-Doppler Lab wins BOKU Invention of the Year 2020 Award
(Vienna, 18.12.2020) Each year, the University of Natural Resources and Life Sciences (BOKU), Vienna awards the most outstanding invention. In 2020, the prize went to our co-inventors from the external module of CCRI´s Christian-Doppler Laboratory…
New method of Coronavirus Decontamination
(Vienna, 17.12.2020) Prof. Thomas Lion, MD, PhD, MSc, of St. Anna Children’s Cancer Research Institute in Vienna and Doc. Ing. Vladimir Scholtz, PhD, of the University of Chemistry and Technology in Prague, are selected for…
Video: Early cancer diagnosis seems crucial in children with immune defect
(Vienna, 03.12.2020) CD27/CD70 deficiencies can lead to cancer in small children: “If diagnosed at an early stage, the majority of these patients are responsive to the hematopoietic stem cell treatment”, says Co-first author Sevgi Köstel…
Cancer in children with rare inborn immune defect: High cure rate if treated early
(Vienna, 03.12.2020) New research data highlight a marked predisposition to lymphoma, a type of cancer, in children harboring specific gene mutations. A significant fraction of these rare mutations also cause inborn immune defects associated with…
Selected for funding: Training a new generation of childhood cancer scientists
(Vienna, 24.11.2020) St. Anna Children’s Cancer Research Institute is part of a European Marie Sklodowska-Curie Actions Innovative Training Network ITN. Being awarded with this grant, Prof. Heinrich Kovar, PhD, is looking forward to train an…
How cancer cells escape crowded tumors
(Vienna, 16.10.2020) When trapped in a crowded environment, cells of the human body try to escape. Scientists now discovered that it is the cell nucleus, which triggers the “evasion reflex”. This reflex is activated once…
How to save lives: Caroline Hutter maps a rare childhood cancer entity
(Vienna, 29.09.2020) Caroline Hutter, MD, PhD, loves to solve tricky puzzles. One of them is Langerhans cell histiocytosis – a disease of which almost nothing was known until a few years ago. Hutter not only…
"Conquer childhood cancer with an army of upgraded immune cells!"
(Vienna, 21.09.2020) Priv.-Doz. René Geyeregger, PhD, is taking full risk on a promising research project. Because this is often the only way to create something groundbreaking. Something that helps children with cancer who no longer…