Next Monday, 21.06.2021 at 19:00 St. Anna Children's Cancer Research Institute (CCRI) is organizing the 2nd panel discussion together with the Wiener Zeitung as part of our FWF project Art4Science (www.art4science.at). Art and science are considered two opposing disciplines from which society expects completely different outputs. In the "Art4Science" project,…
“When cells show up on clothes.” Art4Science Panel Discussion on 21.06.2021
Pediatric high-risk tumors: gene defect shortens survival and needs targeted treatment
(Vienna, 11.06.2021) Neuroblastomas, the most common solid tumors outside the brain in children, are associated with poorer survival if they have genetic alterations in the ALK gene and belong to the high-risk group. This was shown by scientists from St. Anna Children's Cancer Research institute together with colleagues in an…
St. Anna CCRI earns WWTF grant to promote precision medicine in childhood cancer
(Vienna, 08.06.2021) St. Anna Children’s Cancer Research Institute is receiving a prestigious Life Science Grant for Precision Medicine, provided by the Vienna Science and Technology Fund (WWTF). Award winner Eleni Tomazou and her colleagues will clinically validate a promising new diagnostic approach, expected to enable precision medicine in childhood tumors…
Blood test detects childhood tumors based on their epigenetic profiles
(Vienna, 28.05.2021) A new study exploits the characteristic epigenetic signatures of childhood tumors to detect, classify and monitor the disease. The scientists analyzed short fragments of tumor DNA that are circulating in the blood. These “liquid biopsy” analyses exploit the unique epigenetic landscape of bone tumors and do not depend…
Clinical Trials Day: a day to say thank you to pediatric cancer researchers!
(Vienna, 20.05.2021) Today's International Clinical Trials Day is a reminder of the scientific progress enabled by clinical trials. Via clinical research, new medicines and other treatments are made available specifically for children with cancer. St. Anna Children's Cancer Research Institute (St. Anna CCRI) has included more than 16,000 patients in…
Invasive virus infections during chemotherapy: an underestimated factor
(Vienna, 29.04.2021) While the importance of virus infections as a leading cause of morbidity and mortality is well documented in patients undergoing allogeneic stem cell transplantation, their impact in cancer patients receiving chemotherapy is less well studied. A new publication reveals that invasive viral infections can be clinically relevant in…
Day of Immunology – a reminder of the important interplay between immunology and cancer
(Vienna, 29.04.2021) On today’s International Day of Immunology, we would like to draw your attention to the tight interaction between the immune system and cancer development. Despite the introduction of new cancer immunotherapies, this interplay is still not common knowledge. Immunology research has been an integral part of St. Anna…
VR visualization supports research on molecular networks
(Vienna, 23.04.2021) A new VR platform enables the display of huge amounts of data. This can be helpful in the study of rare genetic defects, among other things. Networks offer a powerful way to visualize and analyze complex systems. However, depending on the size and complexity of the network, many…
Immune cells out of control: how lethal hyperinflammation emerges from a novel gene defect
(Vienna, 16.04.2021) Scientists at St. Anna Children’s Cancer Research Institute, together with their collaborators from Finland and Sweden, discover a novel subtype of a genetic disease: genetically determined deficiency of the protein RhoG abrogates the normal cytotoxic function of specific immune cells, causing hemophagocytic lymphohistiocytosis (HLH). These new findings may…
How to improve image analyses of cancer cells
(Vienna, 15.04.2021) New publication on artificial intelligence: Scientists at St. Anna Children‘s Cancer Research Institute present novel insights on automated image analyses of cancer cells. Based on their results the researchers recommend the creation of artificial images to train deep neural networks. Furthermore, they propose methods to effectively segment complex…