2021

Gene defect shortens survival and needs targeted treatment

Pediatric high-risk tumors: gene defect shortens survival and needs targeted treatment Neuroblastomas, the most common solid tumors outside the brain in children, are associated with poorer survival if they have genetic alterations in the ALK gene and belong to the high-risk group. This was shown by scientists from St. Anna Children’s Cancer Research institute together […]

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WWTF grant to promote precision medicine in childhood cancer

St. Anna Children’s Cancer Research Institute is receiving a prestigious Life Science Grant for Precision Medicine, provided by the Vienna Science and Technology Fund (WWTF). Award winner Eleni Tomazou and her colleagues will clinically validate a promising new diagnostic approach, expected to enable precision medicine in childhood tumors based on blood samples.

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Blood test detects childhood tumors based on their epigenetic profiles

Blood test detects childhood tumors based on their epigenetic profiles A new study exploits the characteristic epigenetic signatures of childhood tumors to detect, classify and monitor the disease. The scientists analyzed short fragments of tumor DNA that are circulating in the blood. These “liquid biopsy” analyses exploit the unique epigenetic landscape of bone tumors and

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Invasive virus infections during chemotherapy: an underestimated factor

Invasive virus infections during chemotherapy: an underestimated factor While the importance of virus infections as a leading cause of morbidity and mortality is well documented in patients undergoing allogeneic stem cell transplantation, their impact in cancer patients receiving chemotherapy is less well studied. A new publication reveals that invasive viral infections can be clinically relevant

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ALSF Crazy 8 Initiative Award goes to Vienna: Tracking the tumor origin to cure childhood cancer

The project “Tracking the origin of Ewing sarcoma (…)” coordinated by St. Anna Children’s Cancer Research Institute, has been selected for the prestigious Crazy 8 Initiative Award. With this funding, Viennese scientists aim to elucidate the still unsolved mystery of the origin and development process of pediatric bone sarcomas. This knowledge is fundamental to lay a path for new and more effective therapies to cure childhood cancer.

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