Nerve tumor in children: study identifies better tolerable chemotherapy without loss of efficacy

Nerve tumor in children: study identifies better tolerable chemotherapy without loss of efficacy

(Vienna, 21.06.2021) The initial chemotherapy of aggressive childhood nerve tumors, so-called high-risk neuroblastomas, is crucial for ultimate survival. It has now been shown that the chemotherapy regimen used by the European Neuroblastoma Study Group is equally efficacious but better tolerated than a highly effective regimen from the US. This was…

Hot off the press: a new role for histone modifications in genomic imprinting

Hot off the press: a new role for histone modifications in genomic imprinting

(Vienna, 21.06.2021) Imprinted genes are expressed from either the paternal or maternal allele. Reporting in Nature Communications, scientists led by Martin Leeb have now discovered 71 previously unrecognized imprinted genes in preimplantation blastocysts. The study found that imprinting created by differential histone marks plays a more prominent role in the…