June 2021

a new role for histone modifications in genomic imprinting

Hot off the press: a new role for histone modifications in genomic imprinting Imprinted genes are expressed from either the paternal or maternal allele. Reporting in Nature Communications, scientists led by Martin Leeb have now discovered 71 previously unrecognized imprinted genes in preimplantation blastocysts. The study found that imprinting created by differential histone marks plays

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Gene defect shortens survival and needs targeted treatment

Pediatric high-risk tumors: gene defect shortens survival and needs targeted treatment Neuroblastomas, the most common solid tumors outside the brain in children, are associated with poorer survival if they have genetic alterations in the ALK gene and belong to the high-risk group. This was shown by scientists from St. Anna Children’s Cancer Research institute together

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WWTF grant to promote precision medicine in childhood cancer

St. Anna Children’s Cancer Research Institute is receiving a prestigious Life Science Grant for Precision Medicine, provided by the Vienna Science and Technology Fund (WWTF). Award winner Eleni Tomazou and her colleagues will clinically validate a promising new diagnostic approach, expected to enable precision medicine in childhood tumors based on blood samples.

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