Mutations in SYK cause severe immune disorder with cancer predisposition

Mutations in SYK cause severe immune disorder with cancer predisposition

(Vienna, 29.03.2021) Researchers have deciphered the underlying mechanism of a previously unknown immune disorder that causes severe immune dysfunction involving the intestine, skin, and nervous tissues. The international research team could demonstrate that this disorder is caused by mutations affecting the signaling molecule termed spleen tyrosine kinase (SYK). The newly…