International Childhood Cancer Day: New study on leukemia treatment

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(Vienna, 15.02.2021) Feb 15 is International #ChildhoodCancerDay, a global collaborative campaign to raise awareness about childhood cancer. Scientists at St. Anna Children’s Cancer Research Institute and affiliated clinicians work all year long to improve the chances for children with cancer. A great example is Prof. Christina Peters who recently published a new study on how to treat high-risk acute lymphoblastic leukemia (ALL). 

In their recently published trial FORUM, Christina Peters and colleagues show that total body irradiation (TBI) combined with etoposide is the best conditioning treatment for children with high risk acute lymphoblastic leukemia, in need for a stem cell transplantation.

“We recommend this treatment for children with high risk ALL over 4 years of age, with a sibling or suitable unrelated donor”, says Peters.

As she tells us in the video statement, Christina Peters envisions that innovative therapies – like CAR-T cells – in the future render the burden of transplantation avoidable.

Peters C et al., Journal of Clinical Oncology 2021, Vol. 39, No. 4, Total Body Irradiation or Chemotherapy Conditioning in Childhood ALL: A Multinational, Randomized, Noninferiority Phase III Study